MgSO uptake increased in all maternity units, with the PReCePT program improving overall uptake. Enhanced support did not significantly improve uptake but was associated with better teamwork and understanding among staff.
The study found that children treated with TH showed correlations between their motor performance and white matter connectivity, specifically in areas of the brain associated with motor function. This suggests that TH may help preserve some aspects of motor ability and brain organization, even in the absence of CP. The findings indicate that while TH reduces severe disabilities, it may not fully prevent motor impairments, highlighting the need for ongoing assessment and intervention.
Positive outcomes include increased patient engagement in rehabilitation, improved adherence to rehabilitation protocols, and enhanced neuroplasticity through personalized training that utilizes biological signals in a natural way.
The study indicates that the low-cost virtual reality rehabilitation program will improve postural control in children with cerebral palsy type spastic hemiplegia, with TR being as effective as FtF delivery.
The combination of tSCS and SBLTT led to greater increases in hip and knee extension during gait, improved posture, and reduced spasticity in children with CP. Participants exhibited a more upright posture and better coordination during walking after the intervention.
Improvements in gait pattern and motor control can lead to reduced metabolic power and fatigue in children with CP, enhancing their physical activity levels.
The therapy resulted in decreased co-contraction at the ankle (29 ± 11%, p = 0.02), a more typical plantar flexor activation profile (33 ± 13%, p = 0.01), improved neuromuscular control, a more mechanically-efficient gait pattern (58 ± 34%, p < 0.05), and a reduced metabolic cost of transport (29 ± 15%, p = 0.02). There were also significant increases in neural complexity (5 ± 3%, p = 0.03).
Significant improvement in gross motor function as measured by GMFM-66, with younger children showing greater benefits. Average step counts increased significantly during the intervention.
Identifying associations between fatigue and functional connectivity may lead to improved treatment strategies for fatigue in youth with perinatal stroke.
Participants showed significant improvements in responses to visual perturbations and reduced whole-body sway when receiving SR stimulation, indicating enhanced balance control.
Infants in the Crawli group showed significantly higher scores in gross motor development and specific motor skills compared to control groups. The intervention facilitated the acquisition of mature crawling and positively influenced general development as measured by the Ages and Stages Questionnaires-3 (ASQ-3).
The study found that the TDO and FDO models accurately predicted follow-up foot progression deviations, with TDO showing significant heterogeneity in treatment effects based on baseline foot progression and tibial torsion. The results suggest that these surgical interventions can lead to improved foot alignment and potentially better functional outcomes for children with CP.
Participants experienced a significant increase in step length by 26 ± 13% after the intervention. Three out of four participants showed a direct increase in step length, while one participant had a decrease. The BART model demonstrated good predictive accuracy for step length progression and plateaus in progression.
Both exercise programs led to significant reductions in waist circumference and blood pressure. The Zoom group showed improved aerobic capacity, while the gym group demonstrated superior strength gains. The control group experienced negative health outcomes, including increased BMI and waist circumference.
The implementation of the NPP resulted in a 6.3 percentage point increase in MgSO uptake, reaching 83.1% post-implementation. The program was also found to be cost-effective, generating a net monetary benefit of £866 per preterm baby.
Half of the physicians evaluated the effect of medical cannabinoids as moderate, indicating some level of efficacy in managing symptoms associated with CP.
The study indicates a strong interest among parents and healthcare professionals in cBCIs for children with severe CP, suggesting that these devices could significantly enhance communication capabilities for this population.
Children with neonatal seizures often respond well to antiepileptic treatment. Those with early-onset seizures and recurrent seizures tend to have better treatment responses. Participation in life activities is usually age-appropriate for most children, despite their neurological challenges.
Treatment with intrathecal nicardipine was associated with a reduced odds ratio for developing DCI (0.61) and improved functional outcomes (mRS ≤ 2) with an odds ratio of 2.17 compared to controls.